HuR / ELAVL1 Polyclonal Antibody

Catalog Number:

30702

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q15717
NCBI Gene ID:1994

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

A synthetic peptide of human HuR / ELAVL1 (NP_001410.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.

References:

appl_detail:

WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Datasheet PDF