Product Datasheet
HuR / ELAVL1 Polyclonal Antibody
Catalog Number: 30702
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q15717
NCBI Gene ID:1994
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- A synthetic peptide of human HuR / ELAVL1 (NP_001410.2).
- appl_detail:
- WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:50 - 1:200
- other_names:
- ELAVL1; ELAV1; HUR; Hua; MelG; ELAV-like protein 1
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
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