1-832-868-1888
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Catalog Number: |
29536 |
| other_names: | Dnmt3a; MmuIIIA; DNMT3A2; M.HsaIIIA; TBRS; DNA methyltransferase 3A |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:O88508 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_031898.1). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
IF |
Background: |
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. |
References: |
|
appl_detail: |
IF 1:50 - 1:200 |
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