Product Datasheet
DiMethyl-DNMT3A-K44 pAb
Catalog Number: 29536
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O88508
NCBI Gene ID:13435
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_031898.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- IF 1:50 - 1:200
- other_names:
- Dnmt3a; MmuIIIA; DNMT3A2; M.HsaIIIA; TBRS; DNA methyltransferase 3A
- Purification:
- Affinity purification
- Background:
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
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