Claudin-1 Antibody

Catalog Number:

29226

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95832

Form of Antibody:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Claudin 1

Purification:

Affinity-chromatography

Specificity/Sensitivity:

Claudin 1 antibody detects endogenous levels of total Claudin 1

Applications:

WB IHC

Background:

 Claudin 1 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Acts as a co- receptor for HCV entry into hepatic cells. Belongs to the claudin family. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL. May interact with HCV E1 and E2 proteins.

References:

appl_detail:

WB: 1:500~1:3000

IHC: 1:50~1:200

Datasheet PDF