Product Datasheet  
Claudin-1 Antibody  
Catalog Number: 29226  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O95832
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
  • Storage：  
  • Store at -20°C/1 year
  • Immunogen：  
  • A synthesized peptide derived from human Claudin 1
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • WB: 1:500~1:3000
    IHC: 1:50~1:200
  • other_names：  
  • claudin 1; Claudin-1; CLD1; CLDN1; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1
  • Purification：  
  • Affinity-chromatography
  • Specificity：  
  • Claudin 1 antibody detects endogenous levels of total Claudin 1
  • Applications：  
  • WB IHC
  • Background：  

  •  Claudin 1 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Acts as a co- receptor for HCV entry into hepatic cells. Belongs to the claudin family. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL. May interact with HCV E1 and E2 proteins.




 
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