GADD153 Antibody

Catalog Number:	29163
other_names:	C/EBP-homologous protein, DDIT3, DNA-damage inducible transcript 3, GADD153, Growth arrest and DNA-damage-inducible protein GADD153 Molecular weight: 19174.8 chop
Amount:	100μg
calculated_mw:
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#: P35638
Form of Antibody:	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Immunogen:	A synthesized peptide derived from human GADD153
Purification:	Immunogen affinity purified
Specificity/Sensitivity:	GADD153 Antibody detects endogenous levels of GADD153
Applications:	WB IHC IF/ICC
Background:	CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform.
References:
appl_detail:	WB: 1:500-1:2000 IHC: 1:50-1:200 IF/ICC: 1:100-1:500
	Datasheet PDF

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