Product Datasheet  
GADD153 Antibody  
Catalog Number: 29163  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P35638
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C/1 year
  • Immunogen：  
  • A synthesized peptide derived from human GADD153
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • WB: 1:500-1:2000

    IHC: 1:50-1:200
    IF/ICC: 1:100-1:500
  • other_names：  
  • C/EBP-homologous protein, DDIT3, DNA-damage inducible transcript 3, GADD153, Growth arrest and DNA-damage-inducible protein GADD153 Molecular weight: 19174.8 chop
  • Purification：  
  • Immunogen affinity purified
  • Specificity：  
  • GADD153 Antibody detects endogenous levels of GADD153
  • Applications：  
  • WB IHC IF/ICC
  • Background：  

  •  CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform.




 
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