Cleaved-caspase 3 antibody

Catalog Number:

29034

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P42574

Form of Antibody:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Purification:

Immunogen affinity purified

Specificity/Sensitivity:

Caspase 3 (p17,Cleaved-Asp175) Antibody detects endogenous levels of fragment of activated Caspase 3 resulting from cleavage adjacent to Asp175.

Applications:

WB IHC

Background:

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.

References:

appl_detail:

 WB: 1:500-1:2000

 IHC: 1:50-1:200

Datasheet PDF