Product Datasheet  
Cleaved-caspase 3 antibody  
Catalog Number: 29034  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P42574
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C/1 year
  • Immunogen：  
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  •  WB: 1:500-1:2000

     IHC: 1:50-1:200
  • other_names：  
  • Apopain precursor; CASP-3; CPP-32; CPP32; Caspase-3; Cysteine protease CPP32; ICE3; SCA-1; SREBP cleavage activity 1; Yama protein,p17
  • Purification：  
  • Immunogen affinity purified
  • Specificity：  
  • Caspase 3 (p17,Cleaved-Asp175) Antibody detects endogenous levels of fragment of activated Caspase 3 resulting from cleavage adjacent to Asp175.
  • Applications：  
  • WB IHC
  • Background：  

  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.




 
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