1-832-868-1888
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Catalog Number: |
28468 |
| other_names: | PLP1; GPM6C; HLD1; MMPL; PLP; PLP/DM20; PMD; SPG2; proteolipid protein 1 |
Amount: |
100μg |
| calculated_mw: | 34kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P60201 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human PLP1 (NP_955772.1). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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