Product Datasheet
PLP1 Polyclonal Antibody
Catalog Number: 28468
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P60201
NCBI Gene ID:5354
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human PLP1 (NP_955772.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- PLP1; GPM6C; HLD1; MMPL; PLP; PLP/DM20; PMD; SPG2; proteolipid protein 1
- Purification:
- Affinity purification
- Background:
- This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
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