ERVFRD-1 Polyclonal Antibody

Catalog Number:

27316

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P60508
NCBI Gene ID:405754

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human ERVFRD-1 (NP_997465.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

References:

appl_detail:

WB 1:1000 - 1:4000

Datasheet PDF