Product Datasheet  
ERVFRD-1 Polyclonal Antibody  
Catalog Number: 27316  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P60508
    NCBI Gene ID:405754
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fusion protein of human ERVFRD-1 (NP_997465.1).
  • reactivity：  
  • Human,Mouse,Rat
  • appl_detail：  
  • WB 1:1000 - 1:4000
  • other_names：  
  • ERVFRD-1; ERVFRDE1; GLLL6191; HERV-FRD; HERV-W/FRD; UNQ6191; envFRD; syncytin-2
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.



 
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