MARCKS Polyclonal Antibody

Catalog Number:

27245

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P29966
NCBI Gene ID:4082

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

A synthetic peptide of human MARCKS (NP_002347.5).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF