Product Datasheet
MARCKS Polyclonal Antibody
Catalog Number: 27245
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P29966
NCBI Gene ID:4082
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- A synthetic peptide of human MARCKS (NP_002347.5).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- MARCKS; 80K-L; MACS; PKCSL; PRKCSL; myristoylated alanine-rich C-kinase substrate
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
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