KPNA5 Antibody

Catalog Number:

25411

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O15131
Gene ID:3841

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against an 18 amino acid peptide near the amino terminus of human KPNA5.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

KPNA5 antibody is predicted to not cross-react with other Importin alpha family members.

Applications:

ELISA WB

Background:

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA5 belongs to a subfamily within the KPNA family that also includes KPNA4 and 6 and is thought to be involved in NLS-dependent protein imort into the nucleus.

References:

appl_detail:

Datasheet PDF