TFF3 Antibody

Catalog Number:

25240

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q07654
Gene ID:7033

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 16 amino acid peptide near the carboxy terminus of human TFF3.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

TFF3 antibody is predicted to not cross-react with other TFF family members.

Applications:

ELISA WB IHC

Background:

Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.

References:

appl_detail:

Datasheet PDF