Product Datasheet
TFF3 Antibody
Catalog Number: 25240
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q07654
Gene ID:7033
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 16 amino acid peptide near the carboxy terminus of human TFF3.
- other_names:
- Trefoil factor 3, Intestinal trefoil factor, ITF, P1B
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- TFF3 antibody is predicted to not cross-react with other TFF family members.
- Applications:
- ELISA WB IHC
- Background:
- Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.
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