KLRA3 Antibody

Catalog Number:

24825

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q64329
Gene ID:16634

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 14 amino acid peptide near the carboxy terminus of mouse KLRA3.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

This antibody may cross-react with other LY49 receptors.

Applications:

ELISA WB

Background:

KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.

References:

appl_detail:

Datasheet PDF