Product Datasheet  
KLRA3 Antibody  
Catalog Number: 24825  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q64329
    Gene ID:16634
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 14 amino acid peptide near the carboxy terminus of mouse KLRA3.
  • reactivity：  
  • Ms Rt
  • appl_detail：  
  • other_names：  
  • Killer cell lectin-like receptor subfamily A member 3, Ly49C, Nk2
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • This antibody may cross-react with other LY49 receptors.
  • Applications：  
  • ELISA WB
  • Background：  
  • KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.



 
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