CUEDC1 Antibody

Catalog Number:

24766

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NWM3
Gene ID:404093

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 16 amino acid peptide near the carboxy terminus of human CUEDC1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

CUEDC1 antibody will not cross-react with CUEDC2.

Applications:

ELISA WB IHC

Background:

The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker.

References:

appl_detail:

Datasheet PDF