Product Datasheet  
CUEDC1 Antibody  
Catalog Number: 24766  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q9NWM3
    Gene ID:404093
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 16 amino acid peptide near the carboxy terminus of human CUEDC1.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • CUE Domain-Containing Protein 1
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • CUEDC1 antibody will not cross-react with CUEDC2.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker.



 
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