Carbonic anhydrase 9 antibody

Catalog Number:

22975

Amount:

100μg

Price:

$319

Swiss-Prot No:

NCBI Gene ID: 768
NCBI mRNA#: NM_001216
NCBI Protein#: NP_001207

Form of Antibody:

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage/Stability:

Immunogen:

Synthesized peptide derived from the Internal region of human Carbonic anhydrase 9.

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

WB

Background:

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq]

References:

appl_detail:

Predicted MW: 50kd
Western blotting: 1:500-1:2000

Datasheet PDF