Product Datasheet  
Carbonic anhydrase 9 antibody  
Catalog Number: 22975  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • NCBI Gene ID: 768
    NCBI mRNA#: NM_001216
    NCBI Protein#: NP_001207
  • Form of Antibody：  
  • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Storage：  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen：  
  • Synthesized peptide derived from the Internal region of human Carbonic anhydrase 9.
  • reactivity：  
  • appl_detail：  

  • Predicted MW: 50kd
    Western blotting: 1:500-1:2000

  • other_names：  
  • CAIX; MN
  • Purification：  
  • Purified by antigen-affinity chromatography.
  • Specificity：  
  • Applications：  
  • WB
  • Background：  

  • Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq]




 
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