SQSTM1 antibody

Catalog Number:

22618

Amount:

100μg

Price:

$319

Swiss-Prot No:

NCBI Gene ID: 8878
NCBI mRNA#: NM_003900
NCBI Protein#: NP_003891

Form of Antibody:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

A synthesized peptide derived from human SQSTM1

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

Wb

Background:

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]

References:

appl_detail:

Predicted MW: 48kd
Western blotting: 1:500-1:2000

Datasheet PDF