Product Datasheet  
SQSTM1 antibody  
Catalog Number: 22618  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • NCBI Gene ID: 8878
    NCBI mRNA#: NM_003900
    NCBI Protein#: NP_003891
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen：  
  • A synthesized peptide derived from human SQSTM1
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Predicted MW: 48kd
    Western blotting: 1:500-1:2000

  • other_names：  
  • Purification：  
  • Purified by antigen-affinity chromatography.
  • Specificity：  
  • Applications：  
  • Wb
  • Background：  

  • This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]




 
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