MUS81 antibody

Catalog Number:

22808

Amount:

100μg

Price:

$319

Swiss-Prot No:

NCBI Gene ID: 80198
NCBI mRNA#: NM_025128
NCBI Protein#: NP_079404

Form of Antibody:

Supplied in 1XPBS, 40% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 196 and 380 of MUS81

Purification:

Affinity purified by Protein A.

Specificity/Sensitivity:

Applications:

WB IF

Background:

Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

References:

appl_detail:

Predicted MW: 61kd
Western blotting: 1:500-1:3000
Immunofluorescence: 1:100-1:200

Datasheet PDF