Product Datasheet
MUS81 antibody
Catalog Number: 22808
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- NCBI Gene ID: 80198
NCBI mRNA#: NM_025128
NCBI Protein#: NP_079404
- Form of Antibody:
- Supplied in 1XPBS, 40% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
- Storage:
- Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
- Immunogen:
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 196 and 380 of MUS81
- appl_detail:
- Predicted MW: 61kd
Western blotting: 1:500-1:3000
Immunofluorescence: 1:100-1:200
- Purification:
- Affinity purified by Protein A.
- Background:
- Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
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