Caveolin-2 Antibody 

Catalog Number:

21687

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P51636
Gene ID:858

Form of Antibody:

Storage/Stability:

Immunogen:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total Caveolin-2 protein.

Applications:

WB

Background:

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression.

References:

appl_detail:

Predicted MW: 18 22kd

Western Blot: 1:500~1000

Datasheet PDF