Product Datasheet  
Caveolin-2 Antibody   
Catalog Number: 21687  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P51636
    Gene ID:858
  • Form of Antibody：  
  • Storage：  
  • Immunogen：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 18 22kd

    Western Blot: 1:500~1000

  • other_names：  
  • CAV,
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total Caveolin-2 protein.
  • Applications：  
  • WB
  • Background：  

  • May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression.




 
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