LGR5(GPR49) Antibody

Catalog Number:

21659

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O75473
NCBI Protein: NP_003658.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.490~494(K-I-S-N-Q) derived from Human LGR5(GPR49).

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total LGR5(GPR49) protein.

Applications:

WB

Background:

Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.

Yamamoto Y., Sakamoto M., Fujii G., Tsuiji H. Hepatology 37:528-533(2003)
McClanahan T., Koseoglu S., Smith K. Cancer Biol. Ther. 5:419-426(2006)
Becker L., Huang Q., Mashimo H.Scientific World Journal 8:1168-1176(2008)

References:

appl_detail:

Predicted MW: 95kd
Western blotting: 1:500~1:1000
 

Datasheet PDF