Product Datasheet  
LGR5(GPR49) Antibody  
Catalog Number: 21659  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O75473
    NCBI Protein: NP_003658.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.490~494(K-I-S-N-Q) derived from Human LGR5(GPR49).
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Predicted MW: 95kd
    Western blotting: 1:500~1:1000
     

  • other_names：  
  • FEX; GPR49; GPR67; GRP49; MGC117008
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total LGR5(GPR49) protein.
  • Applications：  
  • WB
  • Background：  

  • Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.

    Yamamoto Y., Sakamoto M., Fujii G., Tsuiji H. Hepatology 37:528-533(2003)
    McClanahan T., Koseoglu S., Smith K. Cancer Biol. Ther. 5:419-426(2006)
    Becker L., Huang Q., Mashimo H.Scientific World Journal 8:1168-1176(2008)




 
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