Dynamin 1 Antibody

Catalog Number:

21653

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q05193
NCBI Protein: NP_001005336.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.774~778(S-P-T-S-S) derived from Human Dynamin 1

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Dynamin 1 protein.

Applications:

WB

Background:

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis "SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis."
Soulet F., Yarar D., Leonard M., Schmid S.L.
Mol. Biol. Cell 16:2058-2067(2005)

References:

appl_detail:

Predicted MW: 100kd
Western blotting: 1:500~1:1000
 

Datasheet PDF