Product Datasheet
Dynamin 1 Antibody
Catalog Number: 21653
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q05193
NCBI Protein: NP_001005336.1
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Immunogen:
- Peptide sequence around aa.774~778(S-P-T-S-S) derived from Human Dynamin 1
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Specificity:
- The antibody detects endogenous levels of total Dynamin 1 protein.
- Background:
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis "SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis."
Soulet F., Yarar D., Leonard M., Schmid S.L.
Mol. Biol. Cell 16:2058-2067(2005)
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