Keratin 7 Antibody

Catalog Number:

21648

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P08729
NCBI Protein: NP_005547.3

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.22~26(A-Q-V-R-L) derived from Human Keratin 7

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Keratin 7 protein.

Applications:

WB

Background:

Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). "Sarcolectin (SCL): structure and expression of the recombinant molecule."

Kaba A., Jiang P., Chany-Fournier F. Biochimie 81:709-715(1999) "Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7."
Lin L., Holbro T., Alonso G. J. Cell. Biochem. 80:483-490(2001) "Translational regulation of human papillomavirus type 16 E7 mRNA by the peptide SEQIKA, shared by rabbit a(1)-globin and human cytokeratin 7."
Kanduc D. J. Virol. 76:7040-7048(2002)

References:

appl_detail:

Predicted MW: 52kd
Western blotting: 1:500~1:1000

Datasheet PDF