Product Datasheet  
Keratin 7 Antibody  
Catalog Number: 21648  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot: P08729
    NCBI Protein: NP_005547.3
  • Form of Antibody:  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen:  
  • Peptide sequence around aa.22~26(A-Q-V-R-L) derived from Human Keratin 7
  • reactivity:  
  • Hu
  • appl_detail:  
  • Predicted MW: 52kd
    Western blotting: 1:500~1:1000
  • other_names:  
  • K7; CK7; SCL; K2C7; MGC3625
  • Purification:  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity:  
  • The antibody detects endogenous levels of total Keratin 7 protein.
  • Applications:  
  • WB
  • Background:  
  • Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). "Sarcolectin (SCL): structure and expression of the recombinant molecule."

    Kaba A., Jiang P., Chany-Fournier F. Biochimie 81:709-715(1999) "Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7."
    Lin L., Holbro T., Alonso G. J. Cell. Biochem. 80:483-490(2001) "Translational regulation of human papillomavirus type 16 E7 mRNA by the peptide SEQIKA, shared by rabbit a(1)-globin and human cytokeratin 7."
    Kanduc D. J. Virol. 76:7040-7048(2002)



 
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