CRABP2 Antibody

Catalog Number:

21647

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P29373
NCBI Protein: NP_001186652.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.87~91(K-W-E-S-E) derived from Human CRABP2

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CRABP2 protein.

Applications:

WB

Background:

Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors "Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest."

Budhu A.S., Noy N. Mol. Cell. Biol. 22:2632-2641(2002) "A ligand-activated nuclear localization signal in cellular retinoic acid binding protein-II."
Sessler R.J., Noy N. Mol. Cell 18:343-353(2005)

References:

appl_detail:

Predicted MW: 16kd
Western blotting: 1:500~1:1000
 

Datasheet PDF