Product Datasheet  
CRABP2 Antibody  
Catalog Number: 21647  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P29373
    NCBI Protein: NP_001186652.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.87~91(K-W-E-S-E) derived from Human CRABP2
  • reactivity：  
  • Hu Rt
  • appl_detail：  

  • Predicted MW: 16kd
    Western blotting: 1:500~1:1000
     

  • other_names：  
  • RBP6; CRABP-II;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous levels of total CRABP2 protein.
  • Applications：  
  • WB
  • Background：  

  • Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors "Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest."

    Budhu A.S., Noy N. Mol. Cell. Biol. 22:2632-2641(2002) "A ligand-activated nuclear localization signal in cellular retinoic acid binding protein-II."
    Sessler R.J., Noy N. Mol. Cell 18:343-353(2005)




 
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