MELK Antibody

Catalog Number:

21625

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q14680
NCBI Protein: NP_055606.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.626~630 (I-R-R-Q-R) derived from Human MELK.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total MELK protein.

Applications:

WB

Background:

Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.

Seong H.-A., Gil M., Kim K.-T., Kim S.-J., Ha H. Biochem. J. 361:597-604(2002)
Vulsteke V., Beullens M., Boudrez A., Keppens S. Biol. Chem. 279:8642-8647(2004)

References:

appl_detail:

Predicted MW: 74kd
Western blotting: 1:500

Datasheet PDF