Product Datasheet  
MELK Antibody  
Catalog Number: 21625  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q14680
    NCBI Protein: NP_055606.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.626~630 (I-R-R-Q-R) derived from Human MELK.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Predicted MW: 74kd
    Western blotting: 1:500

  • other_names：  
  • hPK38; KIAA0175; hMELK
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total MELK protein.
  • Applications：  
  • WB
  • Background：  

  • Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.

    Seong H.-A., Gil M., Kim K.-T., Kim S.-J., Ha H. Biochem. J. 361:597-604(2002)
    Vulsteke V., Beullens M., Boudrez A., Keppens S. Biol. Chem. 279:8642-8647(2004)




 
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