Tubulin b-III Antibody

Catalog Number:

21617

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q13509
NCBI Protein: NP_006077.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.442~446(E-E-S-E-A) derived from Human Tubulin b-III.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total Tubulin b-III protein.

Applications:

WB

Background:

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the a-chain. TUBB3 plays a critical role in proper axon guidance and mantainance.

Tischfield M.A., Baris H.N., Wu C., Rudolph G. Cell 140:74-87(2010)
Katsetos C.D., Legido A., Perentes E., Mork S.J. J. Child Neurol. 18:851-866(2003)

References:

appl_detail:

Predicted MW: 55kd
Western blotting: 1:500~1:1000

Datasheet PDF