Product Datasheet
Tubulin b-III Antibody
Catalog Number: 21617
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q13509
NCBI Protein: NP_006077.2
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Immunogen:
- Peptide sequence around aa.442~446(E-E-S-E-A) derived from Human Tubulin b-III.
- appl_detail:
- Predicted MW: 55kd
Western blotting: 1:500~1:1000
- other_names:
- TUBB4; CFEOM3A; TUBB3
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Specificity:
- The antibody detects endogenous level of total Tubulin b-III protein.
- Background:
- Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the a-chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
Tischfield M.A., Baris H.N., Wu C., Rudolph G. Cell 140:74-87(2010)
Katsetos C.D., Legido A., Perentes E., Mork S.J. J. Child Neurol. 18:851-866(2003)
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