FOXP2 Antibody

Catalog Number:

21608

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O15409
NCBI Protein: NP_055306.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.707~711(E-E-P-L-S) derived from Human FOXP2.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total FOXP2 protein.

Applications:

WB

Background:

Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Involved in neural mechanisms mediating the development of speech and language.

Bruce H.A., Margolis R.L.Hum. Genet. 111:136-144(2002) Teramitsu I., Kudo L.C., London S.E., Geschwind D.H., White S.A.J. Neurosci. 24:3152-3163(2004)

References:

appl_detail:

Predicted MW: 85kd
Western blotting: 1:500~1:1000

Datasheet PDF