Product Datasheet
FOXP2 Antibody
Catalog Number: 21608
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O15409
NCBI Protein: NP_055306.1
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Immunogen:
- Peptide sequence around aa.707~711(E-E-P-L-S) derived from Human FOXP2.
- appl_detail:
- Predicted MW: 85kd
Western blotting: 1:500~1:1000
- other_names:
- SPCH1; CAGH44; TNRC10
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Specificity:
- The antibody detects endogenous level of total FOXP2 protein.
- Background:
- Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Involved in neural mechanisms mediating the development of speech and language.
Bruce H.A., Margolis R.L.Hum. Genet. 111:136-144(2002) Teramitsu I., Kudo L.C., London S.E., Geschwind D.H., White S.A.J. Neurosci. 24:3152-3163(2004)
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