Paxillin(Ab-88) Antibody

Catalog Number:

21538

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P49023
NCBI Protein: NP_001074324.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.86~90 (P-V-Y-G-S) derived from Human Paxillin.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total Paxillin protein.

Applications:

WB IF

Background:

Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).

Burridge, K. et al. (1992) J. Cell Biol. 119, 893-903.
Bellis, S. L. et al. (1995) J. Biol. Chem. 270, 17437-17441
Schaller, M.D. and Parsons, J.T. (1995) Mol. Cell. Biol. 15, 2635-2645.
Turner, C.E. (2000) J. Cell Sci. 113, 4139-4140.

References:

appl_detail:

Predicted MW: 68kd
Western blotting: 1:500~1:1000
Immunofluorescence: 1:50~1:100

Datasheet PDF