Product Datasheet  
Paxillin(Ab-88) Antibody  
Catalog Number: 21538  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot: P49023
    NCBI Protein: NP_001074324.1
  • Form of Antibody:  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen:  
  • Peptide sequence around aa.86~90 (P-V-Y-G-S) derived from Human Paxillin.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Predicted MW: 68kd
    Western blotting: 1:500~1:1000
    Immunofluorescence: 1:50~1:100
  • other_names:  
  • PAXI; PXN;
  • Purification:  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity:  
  • The antibody detects endogenous level of total Paxillin protein.
  • Applications:  
  • WB IF
  • Background:  
  • Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).

    Burridge, K. et al. (1992) J. Cell Biol. 119, 893-903.
    Bellis, S. L. et al. (1995) J. Biol. Chem. 270, 17437-17441
    Schaller, M.D. and Parsons, J.T. (1995) Mol. Cell. Biol. 15, 2635-2645.
    Turner, C.E. (2000) J. Cell Sci. 113, 4139-4140.



 
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