VEGFR2(Ab-1059) Antibody

Catalog Number:

21531

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P35968
NCBI Protein: NP_002244.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa. 1057~1061 (P-D-Y-V-R) derived from Human VEGFR2.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous levels of total VEGFR2 protein.

Applications:

WB

Background:

Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

Zeng H, et al. (2001) J Biol Chem. 276(35): 32714-32719.
Dougher M, et al. (1999) Oncogene. 18(8): 1619-1627.

References:

appl_detail:

Predicted MW: 210 230kd
Western blotting: 1:1000

Datasheet PDF