Product Datasheet  
VEGFR2(Ab-1059) Antibody  
Catalog Number: 21531  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P35968
    NCBI Protein: NP_002244.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa. 1057~1061 (P-D-Y-V-R) derived from Human VEGFR2.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Predicted MW: 210 230kd
    Western blotting: 1:1000
  • other_names：  
  • FLK1; KDR; VGFR2; VGR2; kinase insert domain receptor
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous levels of total VEGFR2 protein.
  • Applications：  
  • WB
  • Background：  
  • Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

    Zeng H, et al. (2001) J Biol Chem. 276(35): 32714-32719.
    Dougher M, et al. (1999) Oncogene. 18(8): 1619-1627.



 
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