stathmin1(Ab-62) Antibody

Catalog Number:

21518

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P16949
NCBI Protein: NP_001138926.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.60~64 (R-K-S-H-E) derived from Human Stathmin 1.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total Stathmin 1 protein.

Applications:

WB IHC

Background:

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear

Marklund, U. et al. (1994) Eur. J. Biochem. 225, 53-60.
Gavet, O. et al. (1998) J. Cell Sci. 111, 3333-3346.
Di Paolo, G. et al. (1996) J. Cell. Biol. 133, 1383-1390.

References:

appl_detail:

Predicted MW: 19kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100

Datasheet PDF